Abstract: Cancer continues to be a major global health concern, affecting millions of lives worldwide. However, translational cancer research has emerged as a crucial approach in the fight against cancer, bridging the gap between laboratory discoveries and clinical applications. This presentation begins by introducing precision medicine and emphasizing the role of cancer biomarkers. The use of proteomic and genomic profiling, along with molecular diagnostics, is essential for identifying cancer subtypes, predicting treatment response, and determining personalized strategies.

Liquid biopsies, which involve the analysis of circulating tumor DNA and other biomarkers in liquid samples, have shown promise for non-invasive cancer detection, monitoring treatment response, and identifying resistance mechanisms. This approach has the potential to revolutionize cancer diagnosis and monitoring.

Despite significant advancements, challenges such as resistance and tumor heterogeneity pose obstacles to long-term treatment success. This presentation will cover research topics such as drug repurposing, artificial intelligence, and the utilization of Chinese medicine in cancer treatment.

Biography: Dr William Cho primarily focused on cancer studies with the aim of identifying biomarkers for cancer diagnosis, treatment prediction, and prognosis. As a seasoned researcher, Dr Cho has contributed over 600 peer-reviewed papers to reputable journals including Lancet, Lancet Oncology, Annals of Oncology, Advanced Science, Journal of Thoracic Oncology, Nature Communications, Cancer Communications, PNAS, Science Advances, Journal of the National Cancer Institute, Journal of Extracellular Vesicles, Clinical Cancer Research, Molecular Cancer, and Theranostics, among others. These publications cover a wide range of topics including cancer biomarkers, non-coding RNAs, extracellular vesicles, drug repurposing and Chinese medicine. Additionally, Dr Cho has crafted over three dozen books, including "MicroRNAs in Cancer Translational Research", "An Omics Perspective on Cancer Research", "Supportive Cancer Care with Chinese Medicine", "Drug Repurposing in Cancer Therapy: Approaches and Applications", “Resistance to Anti-CD20 Antibodies and Approaches for Their Reversal”, and “Biochemical and Molecular Pharmacology in Drug Discovery” to name a few.
Dr Cho published papers have garnered more than 30,000 citations and Dr Cho is being listed in the top 2% most influential scientists in the world since 2017. Recently, Dr Cho is also listed in the Highly Cited Researchers in 2023 by Clarivate.